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Accumulation and Elimination of Enrofloxacin and Ciprofloxacin in Tissues of Shrimp Litopenaeus vannamei under Laboratory and Farm Conditions
Joint Authors
López-Zavala, Alonso Alexis
Gómez-Jiménez, Silvia
Bermúdez-Almada, María del Carmen
Espinosa-Plascencia, Angelica
Flores-Miranda, Brisa Marisol
González-Carrillo, Haydé Hayamaí
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
This study aimed to quantify the accumulation and elimination of Enrofloxacin (ENRO) and Ciprofloxacin (CIPRO) in cultivated Litopenaeus vannamei under controlled laboratory and farm conditions.
Laboratory- and farm-raised shrimp were given feed supplemented with 200 mg/kg ENRO for 14 days, followed by a 16-day diet without antibiotics.
The levels of ENRO and CIPRO were analyzed by High Performance Liquid Chromatography (HPLC).
In the laboratory, ENRO concentrations in the muscle and hepatopancreas reached a maximum (Cmax) of 0.54±0.26 μg/g and 3.52±1.9 μg/g, respectively; Cmax values for CIPRO in the laboratory were 0.18±0.13 μg/g (muscle) and 1.05±0.20 μg/g (hepatopancreas).
In farmed shrimp, Cmax values for ENRO were 0.36±0.17 μg/g muscle and 1.60±0.82 μg/g in the hepatopancreas; CIPRO Cmax values were 0.03±0.02 μg/g (muscle) and 0.36±0.08 μg/g (hepatopancreas).
Two to fourteen days were necessary to eliminate both antibiotics from muscular tissue and four to more fourteen days for complete elimination of the antibiotics from the hepatopancreas.
These results should be considered in terms of minimum concentrations necessary to inhibit Vibrio bacteria to determine whether the current use of this antibiotic is effective in controlling disease.
American Psychological Association (APA)
Flores-Miranda, Brisa Marisol& Espinosa-Plascencia, Angelica& Gómez-Jiménez, Silvia& López-Zavala, Alonso Alexis& González-Carrillo, Haydé Hayamaí& Bermúdez-Almada, María del Carmen. 2012. Accumulation and Elimination of Enrofloxacin and Ciprofloxacin in Tissues of Shrimp Litopenaeus vannamei under Laboratory and Farm Conditions. ISRN Pharmaceutics،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-467010
Modern Language Association (MLA)
Flores-Miranda, Brisa Marisol…[et al.]. Accumulation and Elimination of Enrofloxacin and Ciprofloxacin in Tissues of Shrimp Litopenaeus vannamei under Laboratory and Farm Conditions. ISRN Pharmaceutics No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-467010
American Medical Association (AMA)
Flores-Miranda, Brisa Marisol& Espinosa-Plascencia, Angelica& Gómez-Jiménez, Silvia& López-Zavala, Alonso Alexis& González-Carrillo, Haydé Hayamaí& Bermúdez-Almada, María del Carmen. Accumulation and Elimination of Enrofloxacin and Ciprofloxacin in Tissues of Shrimp Litopenaeus vannamei under Laboratory and Farm Conditions. ISRN Pharmaceutics. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-467010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467010