PPAR Genomics and Pharmacogenomics : Implications for Cardiovascular Disease
Author
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-03-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
The peroxisome proliferator-activated receptors (PPARs) consist of three related transcription factors that serve to regulate a number of cellular processes that are central to cardiovascular health and disease.
Numerous pharmacologic studies have assessed the effects of specific PPAR agonists in clinical trials and have provided insight into the clinical effects of these genes while genetic studies have demonstrated clinical associations between PPAR polymorphisms and abnormal cardiovascular phenotypes.
With the abundance of data available from these studies as a background, PPAR pharmacogenetics has become a promising and rapidly advancing field.
This review focuses on summarizing the current state of understanding of PPAR genetics and pharmacogenetics and the important implications for the individualization of therapy for patients with cardiovascular diseases.
American Psychological Association (APA)
Cresci, Sharon. 2008. PPAR Genomics and Pharmacogenomics : Implications for Cardiovascular Disease. PPAR Research،Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-467033
Modern Language Association (MLA)
Cresci, Sharon. PPAR Genomics and Pharmacogenomics : Implications for Cardiovascular Disease. PPAR Research No. 2008 (2008), pp.1-11.
https://search.emarefa.net/detail/BIM-467033
American Medical Association (AMA)
Cresci, Sharon. PPAR Genomics and Pharmacogenomics : Implications for Cardiovascular Disease. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-11.
https://search.emarefa.net/detail/BIM-467033
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467033