Reactive Oxygen Species in Vascular Formation and Development
Joint Authors
Zhou, Yijiang
Guo, Meiqun
Yan, Hui
Zhang, Li
Xiao, Qingzhong
Zhu, Jianhua
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-22
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Reactive oxygen species (ROS) are derived from the metabolism of oxygen and are traditionally viewed as toxic byproducts that cause damage to biomolecules.
It is now becoming widely acknowledged that ROS are key modulators in a variety of biological processes and pathological states.
ROS mediate key signaling transduction pathways by reversible oxidation of certain signaling components and are involved in the signaling of growth factors, G-protein-coupled receptors, Notch, and Wnt and its downstream cascades including MAPK, JAK-STAT, NF-κB, and PI3K/AKT.
Vascular formation and development is one of the most important events during embryogenesis and is vital for postnasal tissue repair.
In this paper, we will discuss how ROS regulate different steps in vascular development, including smooth muscle cell differentiation, angiogenesis, endothelial progenitor cells recruitment, and vascular cell migration.
American Psychological Association (APA)
Zhou, Yijiang& Yan, Hui& Guo, Meiqun& Zhu, Jianhua& Xiao, Qingzhong& Zhang, Li. 2013. Reactive Oxygen Species in Vascular Formation and Development. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-467085
Modern Language Association (MLA)
Zhou, Yijiang…[et al.]. Reactive Oxygen Species in Vascular Formation and Development. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-14.
https://search.emarefa.net/detail/BIM-467085
American Medical Association (AMA)
Zhou, Yijiang& Yan, Hui& Guo, Meiqun& Zhu, Jianhua& Xiao, Qingzhong& Zhang, Li. Reactive Oxygen Species in Vascular Formation and Development. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-14.
https://search.emarefa.net/detail/BIM-467085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467085