A Brachytherapy Plan Evaluation Tool for Interstitial Applications
Joint Authors
Anbumani, Surega
Anchineyan, Pichandi
Ganesh, Kalaivany
Dayalan, Sridhar
Nambiraj, N. Arunai
Bilimagga, Ramesh S.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Radiobiological metrics such as tumor control probability (TCP) and normal tissue complication probability (NTCP) help in assessing the quality of brachytherapy plans.
Application of such metrics in clinics as well as research is still inadequate.
This study presents the implementation of two indigenously designed plan evaluation modules: Brachy_TCP and Brachy_NTCP.
Evaluation tools were constructed to compute TCP and NTCP from dose volume histograms (DVHs) of any interstitial brachytherapy treatment plan.
The computation module was employed to estimate probabilities of tumor control and normal tissue complications in ten cervical cancer patients based on biologically effective equivalent uniform dose (BEEUD).
The tumor control and normal tissue morbidity were assessed with clinical followup and were scored.
The acute toxicity was graded using common terminology criteria for adverse events (CTCAE) version 4.0.
Outcome score was found to be correlated with the TCP/NTCP estimates.
Thus, the predictive ability of the estimates was quantified with the clinical outcomes.
Biologically effective equivalent uniform dose-based formalism was found to be effective in predicting the complexities and disease control.
American Psychological Association (APA)
Anbumani, Surega& Nambiraj, N. Arunai& Dayalan, Sridhar& Ganesh, Kalaivany& Anchineyan, Pichandi& Bilimagga, Ramesh S.. 2014. A Brachytherapy Plan Evaluation Tool for Interstitial Applications. Advances in Bioinformatics،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-467217
Modern Language Association (MLA)
Anbumani, Surega…[et al.]. A Brachytherapy Plan Evaluation Tool for Interstitial Applications. Advances in Bioinformatics No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-467217
American Medical Association (AMA)
Anbumani, Surega& Nambiraj, N. Arunai& Dayalan, Sridhar& Ganesh, Kalaivany& Anchineyan, Pichandi& Bilimagga, Ramesh S.. A Brachytherapy Plan Evaluation Tool for Interstitial Applications. Advances in Bioinformatics. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-467217
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467217