Pharmacokinetics of the Perioperative Use of Cancer Chemotherapy in Peritoneal Surface Malignancy Patients
Joint Authors
Sugarbaker, Paul H.
Govaerts, K.
Stuart, O. Anthony
Van der Speeten, Kurt
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
The peritoneal surface is an acknowledged locoregional failure site of abdominal malignancies.
Previous treatment attempts with medical therapy alone did not result in long-term survival.
During the last two decades, new treatment protocols combining cytoreductive surgery with perioperative intraperitoneal and intravenous cancer chemotherapy have demonstrated very encouraging clinical results.
This paper aims to clarify the pharmacologic base underlying these treatment regimens.
Materials and Methods.
A review of the current pharmacologic data regarding these perioperative chemotherapy protocols was undertaken.
Conclusions.
There is a clear pharmacokinetic and pharmacodynamic rationale for perioperative intraperitoneal and intravenous cancer chemotherapy in peritoneal surface malignancy patients.
American Psychological Association (APA)
Van der Speeten, Kurt& Govaerts, K.& Stuart, O. Anthony& Sugarbaker, Paul H.. 2012. Pharmacokinetics of the Perioperative Use of Cancer Chemotherapy in Peritoneal Surface Malignancy Patients. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-467284
Modern Language Association (MLA)
Van der Speeten, Kurt…[et al.]. Pharmacokinetics of the Perioperative Use of Cancer Chemotherapy in Peritoneal Surface Malignancy Patients. Gastroenterology Research and Practice No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-467284
American Medical Association (AMA)
Van der Speeten, Kurt& Govaerts, K.& Stuart, O. Anthony& Sugarbaker, Paul H.. Pharmacokinetics of the Perioperative Use of Cancer Chemotherapy in Peritoneal Surface Malignancy Patients. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-467284
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467284