![](/images/graphics-bg.png)
Carbon Dioxide Insufflation in Routine Colonoscopy Is Safe and More Comfortable : Results of a Randomized Controlled Double-Blinded Trial
Joint Authors
Guller, U.
Geyer, M.
Beglinger, C.
Source
Diagnostic and Therapeutic Endoscopy
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Many patients experience pain and discomfort after colonoscopy.
Carbon dioxide (CO2) can reduce periprocedural pain although air insufflation remained the standard procedure.
The objective of this double-blinded, randomized controlled trial was to evaluate whether CO2 insufflation does decrease pain and bloating during and after colonoscopy compared to room air.
Methods.
219 consecutive patients undergoing colonoscopy were randomized to either CO2 or air insufflation.
Propofol was used in all patients for sedation.
Transcutaneous CO2 was continuously measured with a capnograph as a safety parameter.
Pain, bloating, and overall satisfaction were assessed at regular intervals before and after the procedure.
Results(data are mean ±SD).
110 patients were randomized to CO2 and 109 to room air.
The baseline characteristics were similar in both groups.
The mean propofol dose was not different between the treatments, as were the time to reach the ileum and the withdrawal time.
pCO2 at the end of the procedure was 35.2±4.3 mmHg (CO2 group) versus 35.6±6.0 mmHg in the room air group (P>.05).
No relevant complication occurred in either group.
There was significantly less bloating for the CO2 group during the postprocedural recovery period (P<.001) and over the 24-hour period (P<.001).
Also, patients with CO2 insufflation experienced significantly less pain (P=.014).
Finally, a higher overall satisfaction (P=.04 ) was found in the CO2 group.
Conclusions.
This trial provides compelling evidence that CO2 insufflation significantly reduces bloating and pain after routine colonoscopy in propofol-sedated patients.
The procedure is safe with no significant differences in CO2 between the two groups.
American Psychological Association (APA)
Geyer, M.& Guller, U.& Beglinger, C.. 2011. Carbon Dioxide Insufflation in Routine Colonoscopy Is Safe and More Comfortable : Results of a Randomized Controlled Double-Blinded Trial. Diagnostic and Therapeutic Endoscopy،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-467356
Modern Language Association (MLA)
Geyer, M.…[et al.]. Carbon Dioxide Insufflation in Routine Colonoscopy Is Safe and More Comfortable : Results of a Randomized Controlled Double-Blinded Trial. Diagnostic and Therapeutic Endoscopy No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-467356
American Medical Association (AMA)
Geyer, M.& Guller, U.& Beglinger, C.. Carbon Dioxide Insufflation in Routine Colonoscopy Is Safe and More Comfortable : Results of a Randomized Controlled Double-Blinded Trial. Diagnostic and Therapeutic Endoscopy. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-467356
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467356