Perforating Corneal Ulceration in a Patient with Lung Metastatic Adenocarcinoma Treated with Gefitinib : A Case Report
Joint Authors
Ibrahim, Enjie
Dean, William H.
Ayre, Gareth
Sallam, Ahmed
Gomaa, Ahmed
Guglani, Sam
Price, Nicholas
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-18
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We present a case of a sixty-year-old female who presented with sudden onset of painless loss of vision in one eye due to a perforated corneal ulcer, following three months of treatment with gefitinib, a selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor for metastatic adenocarcinoma of the lung with confirmed EGFR gene mutation.
The eye did not show any sign of infection or inflammation and had no associated lid problems to account for the development of corneal ulceration.
The patient went on to have a corneal graft surgery but postoperatively developed corneal graft melt.
This paper aims to raise awareness among ophthalmologists and oncologists of the probable association between gefitinib and corneal ulceration.
American Psychological Association (APA)
Ibrahim, Enjie& Dean, William H.& Price, Nicholas& Gomaa, Ahmed& Ayre, Gareth& Guglani, Sam…[et al.]. 2012. Perforating Corneal Ulceration in a Patient with Lung Metastatic Adenocarcinoma Treated with Gefitinib : A Case Report. Case Reports in Ophthalmological Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-467380
Modern Language Association (MLA)
Ibrahim, Enjie…[et al.]. Perforating Corneal Ulceration in a Patient with Lung Metastatic Adenocarcinoma Treated with Gefitinib : A Case Report. Case Reports in Ophthalmological Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-467380
American Medical Association (AMA)
Ibrahim, Enjie& Dean, William H.& Price, Nicholas& Gomaa, Ahmed& Ayre, Gareth& Guglani, Sam…[et al.]. Perforating Corneal Ulceration in a Patient with Lung Metastatic Adenocarcinoma Treated with Gefitinib : A Case Report. Case Reports in Ophthalmological Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-467380
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467380