Antioxidant Effect of MnTE-2-PyP on Lung in Asthma Mice Model
Joint Authors
Shopova, Veneta
Dancheva, Violeta
Stavreva, Galya
Terziev, Lyudmil
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Aim.
To investigate the effects of MnTE-2-PyP on some markers of antioxidant defence system in asthma mice model.
Material and Methods.
The animals were divided into four groups: group 1, controls; group 2, injected with ovalbumin, group 3, treated with MnTE-2-PyP, and group 4, treated with ovalbumin and MnTE-2-PyP.
The activities of superoxide dismutase, catalase, glutathione peroxidase and nonprotein sulfhydryl groups content (NPSH) were determined in lung homogenate.
Results.
The activities of superoxide dismutase and catalase in group 2 decreased significantly as compared to control group.
The decrease of the same enzymes in group 4 was lower and significant as compared to group 2.
Changes in the glutathione peroxidase activity showed a similar dynamics.
The NPSH groups content decreased in group 2.
In group 4 this decrease was relatively lower as compared to group 2.
Conclusions.
The application of MnTE-2-PyP mitigated the effects of oxidative stress in asthma mice model.
American Psychological Association (APA)
Terziev, Lyudmil& Dancheva, Violeta& Shopova, Veneta& Stavreva, Galya. 2012. Antioxidant Effect of MnTE-2-PyP on Lung in Asthma Mice Model. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-467401
Modern Language Association (MLA)
Terziev, Lyudmil…[et al.]. Antioxidant Effect of MnTE-2-PyP on Lung in Asthma Mice Model. The Scientific World Journal No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-467401
American Medical Association (AMA)
Terziev, Lyudmil& Dancheva, Violeta& Shopova, Veneta& Stavreva, Galya. Antioxidant Effect of MnTE-2-PyP on Lung in Asthma Mice Model. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-467401
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467401
