Fast and Convenient Synthesis of Amine-Terminated Polylactide as a Macroinitiator for ω-Benzyloxycarbonyl-L-Lysine-N-Carboxyanhydrides
Joint Authors
Gong, Feirong
Ju, Mingjie
Cheng, Shujun
Gao, Yun
Source
International Journal of Polymer Science
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-28
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Amine-terminated poly (L-lactide) (NH2-PLLA) with various chain lengths were successfully synthesized by sequential tert-butyl-N-(3-hydroxypropyl) carbamate initiated bulk ring-opening polymerization (ROP) of L-lactide (L-LA) in the presence of Stannous(II) 2-ethylhexanoate (Sn(Oct)2) and deprotection of the N-tert-butoxycarbonyl (Boc) group at the end of the polymer chain.
The polymers obtained were characterized by FT-IR, 1H NMR, and GPC method.
NH2-PLLA thus prepared was used to initiate the polymerization of ω-benzyloxycarbonyl-L-lysine-N-carboxyanhydride (Lys (Z)-NCA), and the result confirmed the high nucleophilicity of the terminal amine group.
This method was not only suitable for the preparation of low molecular weight NH2-PLLA, but also quite efficient in the synthesis of high molecular weight samples.
American Psychological Association (APA)
Ju, Mingjie& Gong, Feirong& Cheng, Shujun& Gao, Yun. 2011. Fast and Convenient Synthesis of Amine-Terminated Polylactide as a Macroinitiator for ω-Benzyloxycarbonyl-L-Lysine-N-Carboxyanhydrides. International Journal of Polymer Science،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-467554
Modern Language Association (MLA)
Ju, Mingjie…[et al.]. Fast and Convenient Synthesis of Amine-Terminated Polylactide as a Macroinitiator for ω-Benzyloxycarbonyl-L-Lysine-N-Carboxyanhydrides. International Journal of Polymer Science No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-467554
American Medical Association (AMA)
Ju, Mingjie& Gong, Feirong& Cheng, Shujun& Gao, Yun. Fast and Convenient Synthesis of Amine-Terminated Polylactide as a Macroinitiator for ω-Benzyloxycarbonyl-L-Lysine-N-Carboxyanhydrides. International Journal of Polymer Science. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-467554
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467554