Glycemic Control after Total Pancreatectomy for Intraductal Papillary Mucinous Neoplasm : An Exploratory Study
Joint Authors
Stauffer, John A.
Meek, Shon E.
Asbun, Horacio J.
Chindris, Ana M.
Nguyen, Justin H.
Woodward, Timothy A.
Jamil, Laith H.
Wallace, Michael B.
Raimondo, Massimo
Scimeca, Daniela
Gill, Kanwar R. S.
Heckman, Michael G.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Glycemic control following total pancreatectomy (TP) has been thought to be difficult to manage.
Diffuse intraductal papillary mucinous neoplasm (IPMN) is a potentially curable precursor to pancreatic adenocarcinoma, best treated by TP.
Objective.
Compare glycemic control in patients undergoing TP for IPMN to patients with type 1 diabetes mellitus (DM).
Design/Setting.
Retrospective cohort.
Outcome Measure.
Hemoglobin A1C(HbA1C) at 6, 12, 18, and 24 months after TP.
In the control group, baseline was defined as 6 months prior to the first HbA1c measure.
Results.
Mean HgbA1C at each point of interest was similar between TP and type I DM patients (6 months (7.5% versus 7.7%, P=0.52), 12 months (7.3% versus 8.0%, P=0.081), 18 months (7.7% and 7.6%, P=0.64), and at 24 months (7.3% versus 7.8%, P=0.10)).
Seven TP patients (50%) experienced a hypoglycemic event compared to 65 type 1 DM patients (65%, P=0.38).
Limitations.
Small number of TP patients, retrospective design, lack of long-termfollowup.
Conclusion.
This suggests that glycemic control following TP for IPMNcan be well managed, similar to type 1 DM patients.
Fear of DM following TP for IPMN should not preclude surgery when TP is indicated.
American Psychological Association (APA)
Jamil, Laith H.& Chindris, Ana M.& Gill, Kanwar R. S.& Scimeca, Daniela& Stauffer, John A.& Heckman, Michael G.…[et al.]. 2012. Glycemic Control after Total Pancreatectomy for Intraductal Papillary Mucinous Neoplasm : An Exploratory Study. HPB Surgery،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-467564
Modern Language Association (MLA)
Jamil, Laith H.…[et al.]. Glycemic Control after Total Pancreatectomy for Intraductal Papillary Mucinous Neoplasm : An Exploratory Study. HPB Surgery No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-467564
American Medical Association (AMA)
Jamil, Laith H.& Chindris, Ana M.& Gill, Kanwar R. S.& Scimeca, Daniela& Stauffer, John A.& Heckman, Michael G.…[et al.]. Glycemic Control after Total Pancreatectomy for Intraductal Papillary Mucinous Neoplasm : An Exploratory Study. HPB Surgery. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-467564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467564