Botulinum Toxin for the Treatment of Myofascial Pain Syndromes Involving the Neck and Back : A Review from a Clinical Perspective
Joint Authors
Martin-del-Rosario, Francisco
Climent, José M.
Kuan, Ta-Shen
Fenollosa, Pedro
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Introduction.
Botulinum toxin inhibits acetylcholine (ACh) release and probably blocks some nociceptive neurotransmitters.
It has been suggested that the development of myofascial trigger points (MTrP) is related to an excess release of ACh to increase the number of sensitized nociceptors.
Although the use of botulinum toxin to treat myofascial pain syndrome (MPS) has been investigated in many clinical trials, the results are contradictory.
The objective of this paper is to identify sources of variability that could explain these differences in the results.
Material and Methods.
We performed a content analysis of the clinical trials and systematic reviews of MPS.
Results and Discussion.
Sources of differences in studies were found in the diagnostic and selection criteria, the muscles injected, the injection technique, the number of trigger points injected, the dosage of botulinum toxin used, treatments for control group, outcome measures, and duration of followup.
The contradictory results regarding the efficacy of botulinum toxin A in MPS associated with neck and back pain do not allow this treatment to be recommended or rejected.
There is evidence that botulinum toxin could be useful in specific myofascial regions such as piriformis syndrome.
It could also be useful in patients with refractory MPS that has not responded to other myofascial injection therapies.
American Psychological Association (APA)
Climent, José M.& Kuan, Ta-Shen& Fenollosa, Pedro& Martin-del-Rosario, Francisco. 2013. Botulinum Toxin for the Treatment of Myofascial Pain Syndromes Involving the Neck and Back : A Review from a Clinical Perspective. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-467576
Modern Language Association (MLA)
Climent, José M.…[et al.]. Botulinum Toxin for the Treatment of Myofascial Pain Syndromes Involving the Neck and Back : A Review from a Clinical Perspective. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-467576
American Medical Association (AMA)
Climent, José M.& Kuan, Ta-Shen& Fenollosa, Pedro& Martin-del-Rosario, Francisco. Botulinum Toxin for the Treatment of Myofascial Pain Syndromes Involving the Neck and Back : A Review from a Clinical Perspective. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-467576
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467576