![](/images/graphics-bg.png)
Calcium and Potassium Channels in Experimental Subarachnoid Hemorrhage and Transient Global Ischemia
Joint Authors
Kamp, Marcel A.
Steiger, Hans-Jakob
Hänggi, Daniel
Schneider, Toni
Dibué, Maxine
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Healthy cerebrovascular myocytes express members of several different ion channel families which regulate resting membrane potential, vascular diameter, and vascular tone and are involved in cerebral autoregulation.
In animal models, in response to subarachnoid blood, a dynamic transition of ion channel expression and function is initiated, with acute and long-term effects differing from each other.
Initial hypoperfusion after exposure of cerebral vessels to oxyhemoglobin correlates with a suppression of voltage-gated potassium channel activity, whereas delayed cerebral vasospasm involves changes in other potassium channel and voltage-gated calcium channels expression and function.
Furthermore, expression patterns and function of ion channels appear to differ between main and small peripheral vessels, which may be key in understanding mechanisms behind subarachnoid hemorrhage-induced vasospasm.
Here, changes in calcium and potassium channel expression and function in animal models of subarachnoid hemorrhage and transient global ischemia are systematically reviewed and their clinical significance discussed.
American Psychological Association (APA)
Kamp, Marcel A.& Dibué, Maxine& Schneider, Toni& Steiger, Hans-Jakob& Hänggi, Daniel. 2012. Calcium and Potassium Channels in Experimental Subarachnoid Hemorrhage and Transient Global Ischemia. Stroke Research and Treatment،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-467653
Modern Language Association (MLA)
Kamp, Marcel A.…[et al.]. Calcium and Potassium Channels in Experimental Subarachnoid Hemorrhage and Transient Global Ischemia. Stroke Research and Treatment No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-467653
American Medical Association (AMA)
Kamp, Marcel A.& Dibué, Maxine& Schneider, Toni& Steiger, Hans-Jakob& Hänggi, Daniel. Calcium and Potassium Channels in Experimental Subarachnoid Hemorrhage and Transient Global Ischemia. Stroke Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-467653
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467653