Multiple Sclerosis Presents with Psychotic Symptoms and Coexists with Hypertrophic Cardiomyopathy
Joint Authors
Asil, Talip
İnce, Bahri
Özcan, Muhammed Emin
Karadeli, Hasan Hüseyin
Source
Case Reports in Neurological Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system.
Psychiatric symptoms are not infrequent during MS, yet onset of MS with psychosis is rarely encountered.
A 27-year-old Caucasian male was admitted due to numbness in his right arm and difficulty in walking.
His clinical and laboratorial exams lead to the MS diagnosis.
Nine months earlier, he also developed psychotic disorder, not otherwise specified (PD-NOS).
His sudden onset of PD-NOS, his rapid and complete response to antipsychotics, and a relatively short interval between psychiatric and neurological signs indicate a high likelihood that PD-NOS was a manifestation of underlying MS.
He also suffers from hypertrophic obstructive cardiomyopathy (HOCM).
The patient’s neurological complaints were recovered with methylprednisolone (1 g/day, i.v.) given for five days.
Glatiramer acetate (1 × 1 tb.s.c.) was prescribed for consolidation and, after nine months of his admission, the patient fully recovered from neurological and psychiatric complaints.
Interestingly, very recent studies indicate specific alpha-actinin antibodies in MS and alpha-actinin mutations cause HOCM.
Thus, concurrence of MS with HOCM can be even a new syndrome, if further genetic studies prove.
American Psychological Association (APA)
Özcan, Muhammed Emin& İnce, Bahri& Karadeli, Hasan Hüseyin& Asil, Talip. 2014. Multiple Sclerosis Presents with Psychotic Symptoms and Coexists with Hypertrophic Cardiomyopathy. Case Reports in Neurological Medicine،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-467745
Modern Language Association (MLA)
Özcan, Muhammed Emin…[et al.]. Multiple Sclerosis Presents with Psychotic Symptoms and Coexists with Hypertrophic Cardiomyopathy. Case Reports in Neurological Medicine No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-467745
American Medical Association (AMA)
Özcan, Muhammed Emin& İnce, Bahri& Karadeli, Hasan Hüseyin& Asil, Talip. Multiple Sclerosis Presents with Psychotic Symptoms and Coexists with Hypertrophic Cardiomyopathy. Case Reports in Neurological Medicine. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-467745
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467745