Discrepancies between Antimullerian Hormone and Follicle Stimulating Hormone in Assisted Reproduction

Abstract EN

Data from 107 women undergoing their first IVF/ICSI were analyzed.

Relationships between antimullerian hormone (AMH) and follicle stimulating hormone (FSH) were analyzed after dividing patients into four groups according to AMH/FSH levels.

Concordance was noted in 57% of women (both AMH/FSH either normal or abnormal) while 43%of women had discordant values (AMH/FSH one hormone normal and the other abnormal).

Group 1 (AMH and FSH in normal range) and group 2 (normal AMH and high FSH) were younger compared to group 3 (low AMH and normal FSH) and group 4 (both AMH/FSH abnormal).

Group 1 showing the best oocyte yield was compared to the remaining three groups.

Groups 3 and 4 required higher dose of gonadotrophins for controlled ovarian hyperstimulation showing their low ovarian reserve.

There was no difference in cycle cancellation, clinical pregnancy, and live birth/ongoing pregnancy rate in all groups.

These tests are useful to predict ovarian response but whether AMH is a substantially better predictor is not yet established.