Correlation between Behavioural and Psychological Symptoms of Alzheimer Type Dementia and Plasma Homocysteine Concentration
Joint Authors
Kong, Lingli
Zheng, Zhanjie
Chen, Hong
Wang, Jindong
Yi, Lei
Yu, Hui
Cui, Weizhen
Wang, Chunxia
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The relationship between plasma homocysteine and behavioral and psychological symptoms of dementia (BPSD) has not been specifically investigated in previous research.
In this study, we compared plasma homocysteine (Hcy) among 40 Alzheimer’s disease (AD) patients with BPSD, 37 AD patients without BPSD, and 39 healthy controls.
Our results evidenced that the plasma homocysteine levels in AD patients with BPSD and without BPSD were higher than healthy controls and that the plasma homocysteine concentration in AD patients with BPSD was the highest among the three groups.
Significant correlation between plasma homocysteine concentration and cognitive decline and duration of dementia was observed, but there was no correlation between BPSD and cognitive dysfunction or duration of dementia.
In conclusion, this study showed for the first time that BPSD were associated with plasma homocysteine concentration in Alzheimer's dementia, and the results supported that hyperhomocysteine may take part in the pathogenesis of BPSD.
American Psychological Association (APA)
Zheng, Zhanjie& Wang, Jindong& Yi, Lei& Yu, Hui& Kong, Lingli& Cui, Weizhen…[et al.]. 2014. Correlation between Behavioural and Psychological Symptoms of Alzheimer Type Dementia and Plasma Homocysteine Concentration. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-467772
Modern Language Association (MLA)
Zheng, Zhanjie…[et al.]. Correlation between Behavioural and Psychological Symptoms of Alzheimer Type Dementia and Plasma Homocysteine Concentration. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-467772
American Medical Association (AMA)
Zheng, Zhanjie& Wang, Jindong& Yi, Lei& Yu, Hui& Kong, Lingli& Cui, Weizhen…[et al.]. Correlation between Behavioural and Psychological Symptoms of Alzheimer Type Dementia and Plasma Homocysteine Concentration. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-467772
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467772
