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Features of Human Herpesvirus-6A and -6B Entry
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily.
HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species.
The process of herpesvirus entry into target cells is complicated, and in the case of HHV-6A and HHV-6B, the detailed mechanism remains to be elucidated, although both viruses are known to enter cells via endocytosis.
In this paper, (1) findings about the cellular receptor and its ligand for HHV-6A and HHV-6B are summarized, and (2) a schematic model of HHV-6A’s replication cycle, including its entry, is presented.
In addition, (3) reports showing the importance of lipids in both the HHV-6A envelope and target-cell membrane for viral entry are reviewed, and (4) glycoproteins involved in cell fusion are discussed.
American Psychological Association (APA)
Maeki, Takahiro& Mori, Yasuko. 2012. Features of Human Herpesvirus-6A and -6B Entry. Advances in Virology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-467810
Modern Language Association (MLA)
Maeki, Takahiro& Mori, Yasuko. Features of Human Herpesvirus-6A and -6B Entry. Advances in Virology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-467810
American Medical Association (AMA)
Maeki, Takahiro& Mori, Yasuko. Features of Human Herpesvirus-6A and -6B Entry. Advances in Virology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-467810
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467810