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Sociodemographic Predictors of Survival in Differentiated Thyroid Cancer : Results from the SEER Database
Joint Authors
Bouvet, Michael
Tran Cao, Hop S.
Chang, David C.
Johnston, Lily E.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Differentiated thyroid carcinoma (DTC) is prognosticated upon a combination of tumor characteristics, such as histology and stage, and patient age.
DTC is also notable for having a strong female predominance.
Using a nationwide database with long follow-up times, we explored the interplay between tumor biology and patient characteristics in predicting mortality.
Methods.
The Surveillance, Epidemiology, and End Results (SEER) registry data 1973–2005 was examined for patients with DTC as their only known malignancy.
Cox multivariate analyses were used to generate mortality hazard ratios to evaluate the effects of age, gender, ethnicity, and marital status.
Results.
We identified 55,995 patients with DTC as their only malignancy.
Consistent with the existing literature, the tumors are primarily diagnosed in women (77.5%), and predominantly affect Caucasians (78.3%).
Female gender had a protective effect resulting in a 37% decrease in mortality.
Age at diagnosis predicted mortality over age 40.
Black ethnicity was associated with a 51% increase in mortality compared to Caucasians.
Conclusion.
Multiple demographic factors predict mortality in patients with DTC after adjusting for tumor characteristics, and they appear to have complex interactions.
Recognizing the importance of these factors may enable clinicians to better tailor therapy.
American Psychological Association (APA)
Johnston, Lily E.& Tran Cao, Hop S.& Chang, David C.& Bouvet, Michael. 2012. Sociodemographic Predictors of Survival in Differentiated Thyroid Cancer : Results from the SEER Database. ISRN Endocrinology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-467866
Modern Language Association (MLA)
Johnston, Lily E.…[et al.]. Sociodemographic Predictors of Survival in Differentiated Thyroid Cancer : Results from the SEER Database. ISRN Endocrinology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-467866
American Medical Association (AMA)
Johnston, Lily E.& Tran Cao, Hop S.& Chang, David C.& Bouvet, Michael. Sociodemographic Predictors of Survival in Differentiated Thyroid Cancer : Results from the SEER Database. ISRN Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-467866
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467866