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Vasculitis in Systemic Sclerosis
Joint Authors
Source
International Journal of Rheumatology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Systemic sclerosis (SSc) is a multiorgan connective tissue disease characterized by autoantibody production and fibroproliferative stenosis of the microvasculature.
The vascoluopathy associated with SSc is considered to be noninflammatory, yet frank vasculitis can complicate SSc, posing diagnostic and therapeutic challenges.
Here, we have reviewed the literature for reports of small-, medium-, and large-vessel vasculitis occurring in SSc.
Amongst 88 reported cases of vasculitis in SSc, patients with ANCA-associated vasculitis appear to present a unique subclass in that they combined typical features of SSc with the renal manifestation of ANCA-associated glomerulonephritis.
Other vasculitic syndromes, including large-vessel vasculitis, Behcet's disease, cryoglobulinemia, and polyarteritis nodosa, are rarely encountered in SSc patients.
ANCA-associated vasculitis needs to be considered as a differential diagnosis in SSc patients presenting with renal insufficiency, as renal manifestations may result from distinct disease processes and require appropriate diagnostic testing and treatment.
American Psychological Association (APA)
Kao, Lily& Weyand, Cornelia. 2010. Vasculitis in Systemic Sclerosis. International Journal of Rheumatology،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-467976
Modern Language Association (MLA)
Kao, Lily& Weyand, Cornelia. Vasculitis in Systemic Sclerosis. International Journal of Rheumatology No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-467976
American Medical Association (AMA)
Kao, Lily& Weyand, Cornelia. Vasculitis in Systemic Sclerosis. International Journal of Rheumatology. 2010. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-467976
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467976