Triple-Negative Breast Cancer : An Update on Neoadjuvant Clinical Trials
Joint Authors
Anders, Carey K.
Adamo, Barbara
Amos, Keith D.
Source
International Journal of Breast Cancer
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Triple-negative breast cancer (TNBC) is an aggressive malignancy with a poor prognosis despite the high rates of response to chemotherapy.
This scenario highlights the need to develop novel therapies and/or treatment strategies to reduce the mortality associated with TNBC.
The neoadjuvant setting provides a model for rapid assessment of treatment efficacy with smaller patient accruals and over shorter periods of time compared to the traditional adjuvant setting.
In addition, a clear surrogate endpoint of improved survival, known as pathologic complete response, already exists in this setting.
Here, we review current data from completed and ongoing neoadjuvant clinical trials for TNBC.
American Psychological Association (APA)
Amos, Keith D.& Adamo, Barbara& Anders, Carey K.. 2012. Triple-Negative Breast Cancer : An Update on Neoadjuvant Clinical Trials. International Journal of Breast Cancer،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-467981
Modern Language Association (MLA)
Amos, Keith D.…[et al.]. Triple-Negative Breast Cancer : An Update on Neoadjuvant Clinical Trials. International Journal of Breast Cancer No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-467981
American Medical Association (AMA)
Amos, Keith D.& Adamo, Barbara& Anders, Carey K.. Triple-Negative Breast Cancer : An Update on Neoadjuvant Clinical Trials. International Journal of Breast Cancer. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-467981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-467981