A Case of Rheumatoid Arthritis and Limited Systemic Sclerosis Overlap Successfully Treated with Tocilizumab for Arthritis and Concomitant Generalized Lymphadenopathy and Primary Biliary Cirrhosis

Joint Authors

Sasaki, Noriko
Wakabayashi, Takayuki
Suzuki, Yasuo
Nakamura, Naoya
Saito, Eiko
Nogi, Shinichi
Yamada, Chiho
Sato, Shinji
Chinen, Naofumi
Honda, Kiri

Source

Case Reports in Rheumatology

Issue

Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2014-04-15

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Diseases

Abstract EN

A 57-year-old woman with rheumatoid arthritis (RA) and limited systemic sclerosis (lSSc) was suspected to have lymphadenopathy and primary biliary cirrhosis (PBC).

Lymph node biopsy showed reactive follicular lymphadenopathy with intrafollicular plasmacyte infiltration that was interleukin-6 positive by immunohistostaining.

Because of gradually worsening arthritis, tocilizumab was administered and arthritis improved markedly.

Interestingly, lymphadenopathy and PBC improved simultaneously.

This suggested that interleukin-6 might play an important role in reactive lymphadenopathy and PBC associated with RA/lSSc.

American Psychological Association (APA)

Saito, Eiko& Sato, Shinji& Nogi, Shinichi& Sasaki, Noriko& Chinen, Naofumi& Honda, Kiri…[et al.]. 2014. A Case of Rheumatoid Arthritis and Limited Systemic Sclerosis Overlap Successfully Treated with Tocilizumab for Arthritis and Concomitant Generalized Lymphadenopathy and Primary Biliary Cirrhosis. Case Reports in Rheumatology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-468014

Modern Language Association (MLA)

Saito, Eiko…[et al.]. A Case of Rheumatoid Arthritis and Limited Systemic Sclerosis Overlap Successfully Treated with Tocilizumab for Arthritis and Concomitant Generalized Lymphadenopathy and Primary Biliary Cirrhosis. Case Reports in Rheumatology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-468014

American Medical Association (AMA)

Saito, Eiko& Sato, Shinji& Nogi, Shinichi& Sasaki, Noriko& Chinen, Naofumi& Honda, Kiri…[et al.]. A Case of Rheumatoid Arthritis and Limited Systemic Sclerosis Overlap Successfully Treated with Tocilizumab for Arthritis and Concomitant Generalized Lymphadenopathy and Primary Biliary Cirrhosis. Case Reports in Rheumatology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-468014

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-468014