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Unusual Occurrence of Rare Lipid-Rich Carcinoma and Conventional Invasive Ductal Carcinoma in the One Breast : Case Report
Joint Authors
Bencat, Marian
Machalekova, Katarina
Kajo, Karol
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 56-year-old woman noticed a palpable mass in her left breast during self-examination.
Patient was admitted to our hospital and malignant bifocal tumour was diagnosed by ultrasonography, digital mammography, magnetic resonance, and core-cut biopsy.
The patient underwent planned conservative surgery (biquadrantectomy) with a sentinel node examination, but after results of the frozen section with positive resection margins and positive sentinel lymph nodes subsequent mastectomy with axillary lymph node dissection were realized.
Histology in the resection specimen revealed two isolated and distinct tumours.
One of the lesions represented conventional invasive ductal carcinoma of histological grade 3, and the second tumour was evaluated as invasive lipid-rich carcinoma, containing tumour cells with clear and foamy cytoplasm.
Lipids in neoplastic cells were detected by Oil Red O staining and ultrastructural examination.
Immunohistochemical analysis of both carcinomas was almost identical with negative steroid receptors, positive staining of HER-2, and p53 and with high proliferation activity (Ki-67).
Mastectomy specimen contained residual foci of invasive ductal carcinoma and dissected axillary lymph nodes were free of metastasis.
Patient underwent first cycles of chemotherapy with paclitaxel and Herceptin together with local radiotherapy and two month after surgery is without any evidence of the disease.
American Psychological Association (APA)
Machalekova, Katarina& Kajo, Karol& Bencat, Marian. 2012. Unusual Occurrence of Rare Lipid-Rich Carcinoma and Conventional Invasive Ductal Carcinoma in the One Breast : Case Report. Case Reports in Pathology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-468099
Modern Language Association (MLA)
Machalekova, Katarina…[et al.]. Unusual Occurrence of Rare Lipid-Rich Carcinoma and Conventional Invasive Ductal Carcinoma in the One Breast : Case Report. Case Reports in Pathology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-468099
American Medical Association (AMA)
Machalekova, Katarina& Kajo, Karol& Bencat, Marian. Unusual Occurrence of Rare Lipid-Rich Carcinoma and Conventional Invasive Ductal Carcinoma in the One Breast : Case Report. Case Reports in Pathology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-468099
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468099