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Synthesis, Antimicrobial, and Anti-HIV1 Activity of Quinazoline-4(3H)-one Derivatives
Joint Authors
Vijayakumar, K.
Thiruneelakandan, G.
Ahamed, A. Jafar
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Science
Abstract EN
The present investigation aims to synthesize 11 compounds of quinazoline-1 derivatives and to test their antimicrobial and anti-HIV1 activities.
A quick-witted method was developed for the synthesis of novel substituted quinazolinone derivatives by summarizing diverse diamines with benzoxazine reactions, and it demonstrated the benefits of typical reactions, handy operation, and outstanding product yields.
These compounds were confirmed by elemental analysis, I R, 1H NMR, 13C NMR, and mass spectra.
Then antimicrobial and anti-HIV1 activities of the compounds were tested in-vitro.
It was found that compounds 7–11 possessed a wide range of anti microbial and anti-HIV1 activity.
American Psychological Association (APA)
Vijayakumar, K.& Ahamed, A. Jafar& Thiruneelakandan, G.. 2013. Synthesis, Antimicrobial, and Anti-HIV1 Activity of Quinazoline-4(3H)-one Derivatives. Journal of Applied Chemistry،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-468121
Modern Language Association (MLA)
Vijayakumar, K.…[et al.]. Synthesis, Antimicrobial, and Anti-HIV1 Activity of Quinazoline-4(3H)-one Derivatives. Journal of Applied Chemistry No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-468121
American Medical Association (AMA)
Vijayakumar, K.& Ahamed, A. Jafar& Thiruneelakandan, G.. Synthesis, Antimicrobial, and Anti-HIV1 Activity of Quinazoline-4(3H)-one Derivatives. Journal of Applied Chemistry. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-468121
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468121