Nonhomologous DNA End Joining in Cell-Free Extracts

Joint Authors

Sharma, Sheetal
Raghavan, Sathees C.

Source

Journal of Nucleic Acids

Issue

Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2010-09-22

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Biology
Medicine

Abstract EN

Among various DNA damages, double-strand breaks (DSBs) are considered as most deleterious, as they may lead to chromosomal rearrangements and cancer when unrepaired.

Nonhomologous DNA end joining (NHEJ) is one of the major DSB repair pathways in higher organisms.

A large number of studies on NHEJ are based on in vitro systems using cell-free extracts.

In this paper, we summarize the studies on NHEJ performed by various groups in different cell-free repair systems.

American Psychological Association (APA)

Sharma, Sheetal& Raghavan, Sathees C.. 2010. Nonhomologous DNA End Joining in Cell-Free Extracts. Journal of Nucleic Acids،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-468199

Modern Language Association (MLA)

Sharma, Sheetal& Raghavan, Sathees C.. Nonhomologous DNA End Joining in Cell-Free Extracts. Journal of Nucleic Acids No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-468199

American Medical Association (AMA)

Sharma, Sheetal& Raghavan, Sathees C.. Nonhomologous DNA End Joining in Cell-Free Extracts. Journal of Nucleic Acids. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-468199

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-468199