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Usefulness of C-Reactive Protein as a Marker for Prediction of Future Coronary Events in the Asian Indian Population : Indian Atherosclerosis Research Study
Joint Authors
Rao, Veena S.
Hebbagodi, Sridhara
Shanker, Jayashree
John, Shibu
Kakkar, Vijay V.
Kadarinarasimhiah, Natesha B.
Source
International Journal of Vascular Medicine
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Inflammation plays a pivotal role in all stages of atherosclerosis.
Numerous inflammatory, lipid, and cytokines markers have been associated with coronary artery disease (CAD) risk but data directly comparing their predictive value are limited.
Studies were carried to elucidate the role of high-sensitivity C-reactive protein (hsCRP), other inflammatory as well as lipid markers and their associations.
Among 1021 subjects, comprising 774 CAD affected members from Indian Atherosclerosis Research Study (IARS), plasma hsCRP levels showed strong correlation with inflammatory markers, namely, IL6 (r=.373; P=<.0001), sPLA2 (r=.544; P=<.0001) as also with fibrinogen (r=.579; P=<.0001).
Levels of hsCRP were higher among subjects affected by CAD who suffered a repeat coronary event as compared to those who remained event free and subjects in the top quartile of hsCRP (>3.58 mg/L) were found to have a fourfold higher risk.
In conclusion, hsCRP appears to be an independent predictor of recurrent CAD events in Asian Indian population.
American Psychological Association (APA)
Rao, Veena S.& Kadarinarasimhiah, Natesha B.& John, Shibu& Hebbagodi, Sridhara& Shanker, Jayashree& Kakkar, Vijay V.. 2010. Usefulness of C-Reactive Protein as a Marker for Prediction of Future Coronary Events in the Asian Indian Population : Indian Atherosclerosis Research Study. International Journal of Vascular Medicine،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-468213
Modern Language Association (MLA)
Rao, Veena S.…[et al.]. Usefulness of C-Reactive Protein as a Marker for Prediction of Future Coronary Events in the Asian Indian Population : Indian Atherosclerosis Research Study. International Journal of Vascular Medicine No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-468213
American Medical Association (AMA)
Rao, Veena S.& Kadarinarasimhiah, Natesha B.& John, Shibu& Hebbagodi, Sridhara& Shanker, Jayashree& Kakkar, Vijay V.. Usefulness of C-Reactive Protein as a Marker for Prediction of Future Coronary Events in the Asian Indian Population : Indian Atherosclerosis Research Study. International Journal of Vascular Medicine. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-468213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468213