Buckysomes : New Nanocarriers for Anticancer Drugs
Joint Authors
Partha, Ranga
Danila, Delia
McManus, Madonna
Little, Tina
Conyers, Jodie
Golunski, Eva
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Pharmacy, Health & Medical Sciences
Economics & Business Administration
Pharmacology
Abstract EN
Buckysomes, liposome-like vesicles comprised of dendritic C60 subunits that self-assemble into unilamellar vesicles, are unique nanovectors that have utility in drug delivery.
We have prepared paclitaxel-embedded buckysomes (PEBs) and examined biodistriubition profiles with commercially available formulations of the drug.
As compared to Abraxane, an albumin-bound formulation of paclitaxel, PEBs showed higher tissue accumulation in the liver and the kidney at 45 and 60 minutes and in the lungs at 30 minutes, making them suitable drug-delivery carriers for short-term therapy to the mentioned organs.
These buckysomes can be further functionalized to specifically deliver paclitaxel to the tumor site.
American Psychological Association (APA)
Danila, Delia& Golunski, Eva& Partha, Ranga& McManus, Madonna& Little, Tina& Conyers, Jodie. 2013. Buckysomes : New Nanocarriers for Anticancer Drugs. Journal of Pharmaceutics،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-468320
Modern Language Association (MLA)
Danila, Delia…[et al.]. Buckysomes : New Nanocarriers for Anticancer Drugs. Journal of Pharmaceutics No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-468320
American Medical Association (AMA)
Danila, Delia& Golunski, Eva& Partha, Ranga& McManus, Madonna& Little, Tina& Conyers, Jodie. Buckysomes : New Nanocarriers for Anticancer Drugs. Journal of Pharmaceutics. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-468320
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468320
