Mesoglycan : Clinical Evidences for Use in Vascular Diseases
Joint Authors
Tufano, Antonella
Di Minno, Matteo Nicola Dario
Arturo, Claudia
Cimino, Ernesto
Di Minno, Giovanni
Di Capua, Mirko
Cerbone, Anna Maria
Source
International Journal of Vascular Medicine
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Vascular glycosaminoglycans (GAG) are essential components of the endothelium and vessel wall and have been shown to be involved in several biologic functions.
Mesoglycan, a natural GAG preparation, is a polysaccharide complex rich in sulphur radicals with strong negative electric charge.
It is extracted from porcine intestinal mucosa and is composed of heparan sulfate, dermatan sulfate, electrophoretically slow-moving heparin, and variable and minimal quantities of chondroitin sulfate.
Data on antithrombotic and profibrinolytic activities of the drug show that mesoglycan, although not indicated in the treatment of acute arterial or venous thrombosis because of the low antithrombotic effect, may be useful in the management of vascular diseases, when combined with antithrombotics in the case of disease of cerebral vasculature, and with antithrombotics and vasodilator drugs in the case of chronic peripheral arterial disease.
The protective effect of mesoglycan in patients with venous thrombosis and the absence of side effects, support the use of GAG in patients with chronic venous insufficiency and persistent venous ulcers, in association with compression therapy (zinc bandages, multiple layer bandages, etc.), elastic compression stockings, and local care, and in the prevention of recurrences in patients with previous DVT following the standard course of oral anticoagulation treatment.
American Psychological Association (APA)
Tufano, Antonella& Arturo, Claudia& Cimino, Ernesto& Di Minno, Matteo Nicola Dario& Di Capua, Mirko& Cerbone, Anna Maria…[et al.]. 2010. Mesoglycan : Clinical Evidences for Use in Vascular Diseases. International Journal of Vascular Medicine،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-468338
Modern Language Association (MLA)
Tufano, Antonella…[et al.]. Mesoglycan : Clinical Evidences for Use in Vascular Diseases. International Journal of Vascular Medicine No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-468338
American Medical Association (AMA)
Tufano, Antonella& Arturo, Claudia& Cimino, Ernesto& Di Minno, Matteo Nicola Dario& Di Capua, Mirko& Cerbone, Anna Maria…[et al.]. Mesoglycan : Clinical Evidences for Use in Vascular Diseases. International Journal of Vascular Medicine. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-468338
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468338