FAD2-DGAT2 Genes Coexpressed in Endophytic Aspergillus fumigatus Derived from Tung Oilseeds
Joint Authors
Wang, Yang-Dong
Cui, Qin-Qin
Zhan, Zhi-Yong
Chen, Yi-Cun
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Recent efforts to genetically engineer plants that contain fatty acid desaturases to produce valuable fatty acids have made only modest progress.
Diacylglycerol acyltransferase 2 (DGAT2), which catalyzes the final step in triacylglycerol (TAG) assembly, might potentially regulate the biosynthesis of desired fatty acids in TAGs.
To study the effects of tung tree (Vernicia fordii) vfDGAT2 in channeling the desired fatty acids into TAG, vfDGAT2 combined with the tung tree fatty acid desaturase-2 (vfFAD2) gene was co-introduced into Aspergillus fumigatus, an endophytic fungus isolated from healthy tung oilseed.
Two transformants coexpressing vfFAD2 and vfDGAT2 showed a more than 6-fold increase in linoleic acid production compared to the original A.
fumigatus strain, while a nearly 2-fold increase was found in the transformant expressing only vfFAD2.
Our data suggest that vfDGAT2 plays a pivotal role in promoting linoleic acid accumulation in TAGs.
This holds great promise for further genetic engineering aimed at producing valuable fatty acids.
American Psychological Association (APA)
Chen, Yi-Cun& Wang, Yang-Dong& Cui, Qin-Qin& Zhan, Zhi-Yong. 2012. FAD2-DGAT2 Genes Coexpressed in Endophytic Aspergillus fumigatus Derived from Tung Oilseeds. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-468340
Modern Language Association (MLA)
Chen, Yi-Cun…[et al.]. FAD2-DGAT2 Genes Coexpressed in Endophytic Aspergillus fumigatus Derived from Tung Oilseeds. The Scientific World Journal No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-468340
American Medical Association (AMA)
Chen, Yi-Cun& Wang, Yang-Dong& Cui, Qin-Qin& Zhan, Zhi-Yong. FAD2-DGAT2 Genes Coexpressed in Endophytic Aspergillus fumigatus Derived from Tung Oilseeds. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-468340
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468340