An Exploration of Apathy and Impulsivity in Parkinson Disease
Joint Authors
Ahearn, David J.
McDonald, Kathryn
Leroi, Iracema
Barraclough, Michelle
Source
Current Gerontology and Geriatrics Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-09
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Apathy and impulsivity in Parkinson disease (PD) are associated with clinically significant behavioral disorders.
Aim.
To explore the phenomenology, distribution, and clinical correlates of these two behaviors.
Methods.
In PD participants (n=99) without dementia we explored the distribution of measures of motivation and impulsivity using univariate methods.
We then undertook factor analysis to define specific underlying dimensions of apathy and impulsivity.
Regression models were developed to determine the associated demographic and clinical features of the derived dimensions.
Results.
The factor analysis of apathy (AES-C) revealed a two-factor solution: “cognitive-behavior” and “social indifference”.
The factor analysis of impulsivity (BIS-11) revealed a five-factor solution: “inattention”; “impetuosity”; “personal security”; “planning”; and “future orientation”.
Apathy was significantly associated with: age, age of motor symptom onset (positive correlation), disease stage, motor symptom severity, and depression.
Impulsivity was significantly associated with: age of motor symptom onset (negative correlation), gambling and anxiety scores, and motor complications.
We observed an overlap of apathy and impulsivity in some participants.
Conclusion.
In PD, apathy and impulsivity have specific phenomenological profiles and are associated with particular clinical phenotypes.
In spite of this, there is some overlap of behaviors which may suggests common aspects in the pathology underlying motivation and reward processes.
American Psychological Association (APA)
Ahearn, David J.& McDonald, Kathryn& Barraclough, Michelle& Leroi, Iracema. 2012. An Exploration of Apathy and Impulsivity in Parkinson Disease. Current Gerontology and Geriatrics Research،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-468346
Modern Language Association (MLA)
Ahearn, David J.…[et al.]. An Exploration of Apathy and Impulsivity in Parkinson Disease. Current Gerontology and Geriatrics Research No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-468346
American Medical Association (AMA)
Ahearn, David J.& McDonald, Kathryn& Barraclough, Michelle& Leroi, Iracema. An Exploration of Apathy and Impulsivity in Parkinson Disease. Current Gerontology and Geriatrics Research. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-468346
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468346