Focal Therapy in the Management of Prostate Cancer : An Emerging Approach for Localized Prostate Cancer
Joint Authors
Mimata, Hiromitsu
Nomura, Takeo
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A widespread screening with prostate-specific antigen (PSA) has led increased diagnosis of localized prostate cancer along with a reduction in the proportion of advanced-stage disease at diagnosis.
Over the past decade, interest in focal therapy as a less morbid option for the treatment of localized low-risk prostate cancer has recently been renewed due to downward stage migration.
Focal therapy stands midway between active surveillance and radical treatments, combining minimal morbidity with cancer control.
Several techniques of focal therapy have potential for isolated ablation of a tumor focus with sparing of uninvolved surround tissue demonstrating excellent short-term cancer control and a favorable patient’s quality of life.
However, to date, tissue ablation has mostly used for near-whole prostate gland ablation without taking advantage of accompanying the technological capabilities.
The available ablative technologies include cryotherapy, high-intensity focused ultrasound (HIFU), and vascular-targeted photodynamic therapy (VTP).
Despite the interest in focal therapy, this technology has not yet been a well-established procedure nor provided sufficient data, because of the lack of randomized trial comparing the efficacy and morbidity of the standard treatment options.
In this paper we briefly summarize the recent data regarding focal therapy for prostate cancer and these new therapeutic modalities.
American Psychological Association (APA)
Nomura, Takeo& Mimata, Hiromitsu. 2012. Focal Therapy in the Management of Prostate Cancer : An Emerging Approach for Localized Prostate Cancer. Advances in Urology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-468417
Modern Language Association (MLA)
Nomura, Takeo& Mimata, Hiromitsu. Focal Therapy in the Management of Prostate Cancer : An Emerging Approach for Localized Prostate Cancer. Advances in Urology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-468417
American Medical Association (AMA)
Nomura, Takeo& Mimata, Hiromitsu. Focal Therapy in the Management of Prostate Cancer : An Emerging Approach for Localized Prostate Cancer. Advances in Urology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-468417
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468417