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Evidences of Protective Potentials of Microdoses of Ultra-High Diluted Arsenic Trioxide in Mice Receiving Repeated Injections of Arsenic Trioxide
Joint Authors
Bhattacharyya, Soumya Sundar
Banerjee, Pathikrit
Pathak, Surajit
Boujedaini, Naoual
Belon, Philippe
Khuda-Bukhsh, Anisur Rahman
Source
Active and Passive Electronic Components
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The present study was undertaken to examine if microdoses of ultra-high diluted arsenic trioxide (a potentized homeopathic remedy, Arsenicum Album 200C, diluted 10-400 times) have hepatoprotective potentials in mice subjected to repeated injections of arsenic trioxide.
Arsenic intoxicated mice were divided into: (i) those receiving Arsenicum Album-200C daily, (ii) those receiving the same dose of diluted succussed alcohol (Alc 200C) and (iii) another group receiving neither drug nor succussed alcohol.
Two other control groups were also maintained: one fed normal diet only and the other receiving normal diet and Alc-200C.
Toxicity biomarkers like aspartate and alanine aminotransferases, glutathione reductase, catalase, succinate dehydrogenase, superoxide dismutase and reduced glutathione contents were periodically assayed keeping the observer “blinded”.
Additionally, electron microscopic studies and gelatin zymography for matrix metalloproteinases of liver tissues were made at day 90 and 120.
Blood glucose, hemoglobin, estradiol and testosterone contents were also studied.
Compared to controls, Arsenicum Album-200C fed mice showed positive modulations of all parameters studied, thereby providing evidence of protective potentials of the homeopathic drug against chronic arsenic poisoning.
American Psychological Association (APA)
Banerjee, Pathikrit& Bhattacharyya, Soumya Sundar& Pathak, Surajit& Boujedaini, Naoual& Belon, Philippe& Khuda-Bukhsh, Anisur Rahman. 2011. Evidences of Protective Potentials of Microdoses of Ultra-High Diluted Arsenic Trioxide in Mice Receiving Repeated Injections of Arsenic Trioxide. Active and Passive Electronic Components،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-468463
Modern Language Association (MLA)
Banerjee, Pathikrit…[et al.]. Evidences of Protective Potentials of Microdoses of Ultra-High Diluted Arsenic Trioxide in Mice Receiving Repeated Injections of Arsenic Trioxide. Active and Passive Electronic Components No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-468463
American Medical Association (AMA)
Banerjee, Pathikrit& Bhattacharyya, Soumya Sundar& Pathak, Surajit& Boujedaini, Naoual& Belon, Philippe& Khuda-Bukhsh, Anisur Rahman. Evidences of Protective Potentials of Microdoses of Ultra-High Diluted Arsenic Trioxide in Mice Receiving Repeated Injections of Arsenic Trioxide. Active and Passive Electronic Components. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-468463
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468463