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Circulating Tumor Cells in Gastrointestinal Malignancies : Current Techniques and Clinical Implications
Joint Authors
Lurje, Georg
Claudius Hoffmann, Andreas
Schneider, Paul Magnus
Schiesser, Marc
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-11-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Since their introduction more than 50 years by Engell, circulating tumor cells (CTCs) have been evaluated in cancer patients and their detection has been correlated with clinical outcome, in esophageal, gastric, and colorectal cancer.
With the availability of refined technologies, the identification of CTCs from peripheral blood is emerging as a useful tool for the detection of malignancy, monitoring disease progression, and measuring response to therapy.
However, increasing evidence suggests a variety of factors to be responsible for disease progression.
The analysis of a single CTC marker is therefore unlikely to accurately predict progression of disease with sufficient resolution and reproducibility.
Here we discuss the current concept of CTCs, summarize the available techniques for their detection and characterization, and aim to provide a comprehensive update on the clinical implications of CTCs in gastrointestinal (GI) malignancies.
American Psychological Association (APA)
Lurje, Georg& Schiesser, Marc& Claudius Hoffmann, Andreas& Schneider, Paul Magnus. 2009. Circulating Tumor Cells in Gastrointestinal Malignancies : Current Techniques and Clinical Implications. Journal of Oncology،Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-468550
Modern Language Association (MLA)
Lurje, Georg…[et al.]. Circulating Tumor Cells in Gastrointestinal Malignancies : Current Techniques and Clinical Implications. Journal of Oncology No. 2010 (2010), pp.1-9.
https://search.emarefa.net/detail/BIM-468550
American Medical Association (AMA)
Lurje, Georg& Schiesser, Marc& Claudius Hoffmann, Andreas& Schneider, Paul Magnus. Circulating Tumor Cells in Gastrointestinal Malignancies : Current Techniques and Clinical Implications. Journal of Oncology. 2009. Vol. 2010, no. 2010, pp.1-9.
https://search.emarefa.net/detail/BIM-468550
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468550