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Improvement of Aminopeptidase Activity of Dizinc(II) Complexes by Increasing Substrate Accessibility
Joint Authors
Sakiyama, Hiroshi
Suzuki, Keisuke
Hossain, Md. Jamil
Igarashi, Yasuhiro
Aimono, Kei-ichiro
Tone, Katsuya
Wada, Akinobu
Source
International Journal of Inorganic Chemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-02
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A new dizinc(II) complex, [Zn2(bhmp)(MeCO2)2]BPh4 [(bhmp)−: 2,6-bis[bis(2-hydroxyethyl)aminomethyl]-4-methylphenolate anion], performs aminopeptidase activity to hydrolyze L-leucine-p-nitroanilide.
As compared with a related dizinc(II) complex [Zn2(bomp)(MeCO2)2]BPh4 [(bomp)−: 2,6-bis[bis(2-methoxyethyl)aminomethyl]-4-methylphenolate anion], the activity of the present bhmp complex was about 80 times greater than that of the bomp complex.
This is mainly because the substrate accessibility was improved by changing the terminal methoxy groups to hydroxyl groups.
American Psychological Association (APA)
Hossain, Md. Jamil& Wada, Akinobu& Igarashi, Yasuhiro& Aimono, Kei-ichiro& Suzuki, Keisuke& Tone, Katsuya…[et al.]. 2011. Improvement of Aminopeptidase Activity of Dizinc(II) Complexes by Increasing Substrate Accessibility. International Journal of Inorganic Chemistry،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-468758
Modern Language Association (MLA)
Hossain, Md. Jamil…[et al.]. Improvement of Aminopeptidase Activity of Dizinc(II) Complexes by Increasing Substrate Accessibility. International Journal of Inorganic Chemistry No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-468758
American Medical Association (AMA)
Hossain, Md. Jamil& Wada, Akinobu& Igarashi, Yasuhiro& Aimono, Kei-ichiro& Suzuki, Keisuke& Tone, Katsuya…[et al.]. Improvement of Aminopeptidase Activity of Dizinc(II) Complexes by Increasing Substrate Accessibility. International Journal of Inorganic Chemistry. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-468758
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468758