The Cell Wall Teichuronic Acid Synthetase (TUAS) Is an Enzyme Complex Located in the Cytoplasmic Membrane of Micrococcus luteus
Joint Authors
Alexander, Alice A.
Lei, Sijin
Anderson, John S.
Deng, Lingyi Lynn
Source
Biochemistry Research International
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-04-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The cell wall teichuronic acid (TUA) of Micrococcus luteus is a long-chain polysaccharide composed of disaccharide repeating units [-4-β-D-ManNAcAp-(1→6)α-D-Glcp−1-]n, which is covalently anchored to the peptidoglycan on the inner cell wall and extended to the outer surface of the cell envelope.
An enzyme complex responsible for the TUA chain biosynthesis was purified and characterized.
The 440 kDa enzyme complex, named teichuronic acid synthetase (TUAS), is an octomer composed of two kinds of glycosyltransferases, Glucosyltransferase, and ManNAcA-transferase, which is capable of catalyzing the transfer of disaccharide glycosyl residues containing both glucose and the N-acetylmannosaminuronic acid residues.
TUAS displays hydrophobic properties and is found primarily associated with the cytoplasmic membrane.
The purified TUAS contains carotinoids and lipids.
TUAS activity is diminished by phospholipase digestion.
We propose that TUAS serves as a multitasking polysaccharide assembling station on the bacterial membrane.
American Psychological Association (APA)
Deng, Lingyi Lynn& Alexander, Alice A.& Lei, Sijin& Anderson, John S.. 2010. The Cell Wall Teichuronic Acid Synthetase (TUAS) Is an Enzyme Complex Located in the Cytoplasmic Membrane of Micrococcus luteus. Biochemistry Research International،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-468785
Modern Language Association (MLA)
Deng, Lingyi Lynn…[et al.]. The Cell Wall Teichuronic Acid Synthetase (TUAS) Is an Enzyme Complex Located in the Cytoplasmic Membrane of Micrococcus luteus. Biochemistry Research International No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-468785
American Medical Association (AMA)
Deng, Lingyi Lynn& Alexander, Alice A.& Lei, Sijin& Anderson, John S.. The Cell Wall Teichuronic Acid Synthetase (TUAS) Is an Enzyme Complex Located in the Cytoplasmic Membrane of Micrococcus luteus. Biochemistry Research International. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-468785
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468785