Water Chreodes and the Mechanisms of Ligand Diffusion, General Anesthesia, and Sleep
Author
Source
Biochemistry Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The concept of the presence of passageways, chreodes, created by the influence of the hydropathic states of amino acid side chains on the surface water of proteins, has been proposed.
These chreodes facilitate and direct the diffusion of neurotransmitters through surface water, to the receptor or active site on a protein.
This system of chreodes is vulnerable to the presence of some other molecules that may encounter the chreode system.
This encounter and disruption has been proposed to explain the mechanism of general anesthesia.
Based on much recent evidence of the similarities between anesthesia from volatile anesthetic agents and sleep, a comparable mechanism has been proposed for sleep.
Since this must be an exogenous substance to be comparable to a general anesthetic agent, it was proposed that this exogenous, sleep-producing substance is elemental nitrogen.
Recent evidence supports these hypotheses.
American Psychological Association (APA)
Kier, Lemont B.. 2011. Water Chreodes and the Mechanisms of Ligand Diffusion, General Anesthesia, and Sleep. Biochemistry Research International،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-468859
Modern Language Association (MLA)
Kier, Lemont B.. Water Chreodes and the Mechanisms of Ligand Diffusion, General Anesthesia, and Sleep. Biochemistry Research International No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-468859
American Medical Association (AMA)
Kier, Lemont B.. Water Chreodes and the Mechanisms of Ligand Diffusion, General Anesthesia, and Sleep. Biochemistry Research International. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-468859
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468859