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Screening for Thyroid Dysfunction in Pregnancy : Is It Worthwhile?
Author
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
There is a high incidence of thyroid dysfunction during pregnancy resulting in adverse maternal (miscarriages, anaemia in pregnancy, preeclampsia, abruptio placenta and post-partum haemorrhage) and fetal effects (premature birth, low birth weight, increased neonatal respiratory distress) which may justify screening for thyroid function during early pregnancy with interventional levothyroxine therapy for thyroid hypofunction.
There is a greater prevalence of subclinical hypothyroidism in women with delivery before 32 weeks and there is even an association between thyroid autoimmunity and adverse obstetric outcome, which is independent of thyroid function.
Higher maternal TSH levels even within the normal reference range are associated with an increased risk of miscarriages, fetal and neonatal distress and preterm delivery.
There are few prospective randomised trials to substantiate the benefit of screening and the recently reported CATS study did not show a benefit in child IQ at age 3 years.
Nevertheless there seems to be a case for screening to prevent adverse obstetric outcomes.
The clinical epidemiological evidence base does not justify universal screening at the present time.
However, it is probable that more evidence will be produced which may alter this view in the future.
American Psychological Association (APA)
Lazarus, John H.. 2011. Screening for Thyroid Dysfunction in Pregnancy : Is It Worthwhile?. Journal of Thyroid Research،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-468892
Modern Language Association (MLA)
Lazarus, John H.. Screening for Thyroid Dysfunction in Pregnancy : Is It Worthwhile?. Journal of Thyroid Research No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-468892
American Medical Association (AMA)
Lazarus, John H.. Screening for Thyroid Dysfunction in Pregnancy : Is It Worthwhile?. Journal of Thyroid Research. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-468892
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468892