Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The photopic negative response (PhNR) in response to a brief flash is a negative-going wave following the b-wave of the cone electroretinogram (ERG) that is driven by retinal ganglion cells (RGCs).
The function of RGCs is objectively evaluated by analysing the PhNR.
We reviewed articles regarding clinical use of the PhNR.
The PhNR was well correlated with the visual sensitivity obtained by standard automated perimetry and morphometric parameters of the inner retina and optic nerve head in optic nerve and retinal diseases.
Moreover, combining the PhNR with focal or multifocal ERG techniques enables the objective assessment of local function of RGCs.
The PhNR is therefore likely to become established as an objective functional test for optic nerve and retinal diseases involving RGC injury.
American Psychological Association (APA)
Machida, Shigeki. 2012. Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases. Journal of Ophthalmology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-468914
Modern Language Association (MLA)
Machida, Shigeki. Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases. Journal of Ophthalmology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-468914
American Medical Association (AMA)
Machida, Shigeki. Clinical Applications of the Photopic Negative Response to Optic Nerve and Retinal Diseases. Journal of Ophthalmology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-468914
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468914