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Tophaceous Gout and Renal Insufficiency : A New Solution for an Old Therapeutic Dilemma
Joint Authors
Aringer, Martin
Wunderlich, Carsten
Tausche, Anne-Kathrin
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-14
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
The prevalence of gout is increasing with increased life expectancy.
Approximately half of the patients with gout have some degree of renal impairment.
If both conditions persistently coexist, and in severe tophaceous gout, in particular, treatment has been difficult.
We here report on the case of an 87-year-old woman, who had been suffering from recurrent gouty arthritis over 4 years.
Monthly polyarthritis attacks were accompanied by subcutaneous tophi.
Serum uric acid levels were constantly above 600 μmol/L (10 mg/dL).
Allopurinol was no option because of intolerance, while benzbromarone was ineffective because of renal impairment.
Therefore, the novel xanthin oxidase inhibitor febuxostat was started, achieving rapid control of serum urate levels (<360 μmol/L).
After initial worsening of inflammation in the first weeks, gouty attacks stopped and all tophi resolved within the following 10 months.
Renal function remained stable.
American Psychological Association (APA)
Tausche, Anne-Kathrin& Wunderlich, Carsten& Aringer, Martin. 2011. Tophaceous Gout and Renal Insufficiency : A New Solution for an Old Therapeutic Dilemma. Case Reports in Medicine،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-468949
Modern Language Association (MLA)
Tausche, Anne-Kathrin…[et al.]. Tophaceous Gout and Renal Insufficiency : A New Solution for an Old Therapeutic Dilemma. Case Reports in Medicine No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-468949
American Medical Association (AMA)
Tausche, Anne-Kathrin& Wunderlich, Carsten& Aringer, Martin. Tophaceous Gout and Renal Insufficiency : A New Solution for an Old Therapeutic Dilemma. Case Reports in Medicine. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-468949
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468949