Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories
Joint Authors
Machado, Diana
Ramos, Jorge
Narciso, Inácio
Coelho, Elizabeth
Viegas, Sofia
Cadir, Nureisha
Couto, Isabel
Viveiros, Miguel
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We evaluate the performance of the TBcID assay in a panel of 100 acid-fast bacilli cultures.
Sixty-four isolates were TBcID positive for Mycobacterium tuberculosis complex (MTBC), whereas 36 gave negative results.
These included 28 nontuberculous mycobacteria, one nonmycobacterial isolate, one M.
tuberculosis, and six M.
bovis BCG strains.
This corresponds to a sensitivity of 90.14%, specificity of 100%, and positive and negative predictive values of 100% and 80.55%, respectively.
The test is rapid, easy to perform and interpret, and does not require sample preparation or instrumentation.
However, a negative result does not exclude the presence of a strain belonging to MTBC, especially when mutations in mpb64 gene are present or some M.
bovis BCG strains are isolated.
The TBcID showed potential to assist in the identification of MTBC when the implementation and usage of molecular methods are often not possible, principally in resource-limited countries.
American Psychological Association (APA)
Machado, Diana& Ramos, Jorge& Couto, Isabel& Cadir, Nureisha& Narciso, Inácio& Coelho, Elizabeth…[et al.]. 2014. Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-468984
Modern Language Association (MLA)
Machado, Diana…[et al.]. Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-468984
American Medical Association (AMA)
Machado, Diana& Ramos, Jorge& Couto, Isabel& Cadir, Nureisha& Narciso, Inácio& Coelho, Elizabeth…[et al.]. Assessment of the BD MGIT TBc Identification Test for the Detection of Mycobacterium tuberculosis Complex in a Network of Mycobacteriology Laboratories. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-468984
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468984