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Ultrahigh-Field MR (7 T) Imaging of Brain Lesions in Neuromyelitis Optica
Joint Authors
Ge, Yulin
Kister, Ilya
Zhou, Yongxia
Herbert, Joseph
Source
Multiple Sclerosis International
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Brain lesions are common in neuromyelitis optica spectrum disorder (NMOsd) and may resemble lesions of multiple sclerosis (MS).
Objectives.
To describe the imaging characteristics of supratentorial lesions in NMOsd on ultrahigh-field (7 T) MRI with special attention to vessel-lesion relationship.
Methods.
Ten NMOsd patients, all women and all seropositive for NMO IgG, with mean age of 51.3 ± 15.4 years and disease duration of 9.2 ± 6.4 years, were scanned at a 7 T whole-body human MR system with high-resolution 2D gradient echo sequence optimized to best visualize lesions and venous structures, T2- and T1-weighted imaging.
Results.
In 10 patients with NMOsd, a total of 92 lesions were observed (mean: 9.2 ± 8.8; range: 2–30), but only 8 lesions (9%) were traversed by a central venule.
All lesions were <5 mm in diameter, and 83% were located in subcortical white matter.
There were no lesions in the cortex or basal ganglia.
Two patients exhibited diffuse periependymal abnormalities on FLAIR.
Conclusions.
Small, subcortical lesions without a central venule are the most consistent finding of NMOsd on 7 T MRI of the brain.
Ultrahigh-field imaging may be useful for differentiating between NMOsd and MS.
American Psychological Association (APA)
Kister, Ilya& Herbert, Joseph& Zhou, Yongxia& Ge, Yulin. 2013. Ultrahigh-Field MR (7 T) Imaging of Brain Lesions in Neuromyelitis Optica. Multiple Sclerosis International،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-468999
Modern Language Association (MLA)
Kister, Ilya…[et al.]. Ultrahigh-Field MR (7 T) Imaging of Brain Lesions in Neuromyelitis Optica. Multiple Sclerosis International No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-468999
American Medical Association (AMA)
Kister, Ilya& Herbert, Joseph& Zhou, Yongxia& Ge, Yulin. Ultrahigh-Field MR (7 T) Imaging of Brain Lesions in Neuromyelitis Optica. Multiple Sclerosis International. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-468999
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-468999