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Molecular and Other Novel Advances in Treatment of Metastatic Epithelial and Medullary Thyroid Cancers
Joint Authors
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
An understanding of the mutations of the proto-oncogenes and tumor suppressor genes that occur in thyroid cancers should eventually explain the diverse clinical characteristics of these tumors and also direct therapy.
Some insights have already emerged in the last decade; some abnormalities in tumor genes are consistently associated with specific clinical and pathologic findings.
These genetic abnormalities usually represent somatic mutations in tumors of follicular epithelial origin, as opposed to inherited mutations in medullary thyroid cancers of parafollicular C cells origin because most thyroid tumors are sporadic and not familial.
This is different from the multiple endocrine neoplasia syndromes in which the primary tumorigenic gene mutations are inherited.
This improved understanding of the molecular basis of these diseases has led to the development of novel targeted therapeutic approaches which will be discussed in this paper.
American Psychological Association (APA)
Tai, David& Poon, Donald. 2010. Molecular and Other Novel Advances in Treatment of Metastatic Epithelial and Medullary Thyroid Cancers. Journal of Oncology،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-469032
Modern Language Association (MLA)
Tai, David& Poon, Donald. Molecular and Other Novel Advances in Treatment of Metastatic Epithelial and Medullary Thyroid Cancers. Journal of Oncology No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-469032
American Medical Association (AMA)
Tai, David& Poon, Donald. Molecular and Other Novel Advances in Treatment of Metastatic Epithelial and Medullary Thyroid Cancers. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-469032
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469032