The Molecular Genetics of Autism Spectrum Disorders : Genomic Mechanisms, Neuroimmunopathology, and Clinical Implications
Author
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-17
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Autism spectrum disorders (ASDs) have become increasingly common in recent years.
The discovery of single-nucleotide polymorphisms and accompanying copy number variations within the genome has increased our understanding of the architecture of the disease.
These genetic and genomic alterations coupled with epigenetic phenomena have pointed to a neuroimmunopathological mechanism for ASD.
Model animal studies, developmental biology, and affective neuroscience laid a foundation for dissecting the neural pathways impacted by these disease-generating mechanisms.
The goal of current autism research is directed toward a systems biological approach to find the most basic genetic and environmental causes to this severe developmental disease.
It is hoped that future genomic and neuroimmunological research will be directed toward finding the road toward prevention, treatment, and cure of ASD.
American Psychological Association (APA)
Guerra, Daniel J.. 2011. The Molecular Genetics of Autism Spectrum Disorders : Genomic Mechanisms, Neuroimmunopathology, and Clinical Implications. Autism Research and Treatment،Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-469043
Modern Language Association (MLA)
Guerra, Daniel J.. The Molecular Genetics of Autism Spectrum Disorders : Genomic Mechanisms, Neuroimmunopathology, and Clinical Implications. Autism Research and Treatment No. 2011 (2011), pp.1-16.
https://search.emarefa.net/detail/BIM-469043
American Medical Association (AMA)
Guerra, Daniel J.. The Molecular Genetics of Autism Spectrum Disorders : Genomic Mechanisms, Neuroimmunopathology, and Clinical Implications. Autism Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-16.
https://search.emarefa.net/detail/BIM-469043
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469043