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Increased Porphyrins in Primary Liver Cancer Mainly Reflect a Parallel Liver Disease
Joint Authors
Kaczynski, Jerzy
Hansson, Göran
Wallerstedt, Sven
Source
Gastroenterology Research and Practice
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-10-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Hepatic porphyries have been associated with an increased risk of primary liver cancer (PLC), which on the other hand may cause an increased porphyrin production.
To evaluate the role of an underlying liver disorder we analyzed porphyrins in patients with hepatocellular carcinoma (HCC) (n=65), cholangiocellular carcinoma (n=3), or suspected PLC, which turned out to be metastases (n=18) or a benign disorder (n=11).
None of the patients had a family history of porphyry or clinical signs of porphyry.
Increased aminolevulinic acid or porphyrin values were common not only in patients with PLC (43%) but also in metastatic (50%) and benign (64%) liver disorders.
The corresponding proportion for HCC patients with liver cirrhosis (55%) was higher (P<.05) than in those without cirrhosis (17%).
We conclude that symptomatic porphyries are unusual in PLC, whereas elevated urinary and/or faecal porphyrins are common, primarily reflecting a parallel liver disease and not the PLC.
American Psychological Association (APA)
Kaczynski, Jerzy& Hansson, Göran& Wallerstedt, Sven. 2009. Increased Porphyrins in Primary Liver Cancer Mainly Reflect a Parallel Liver Disease. Gastroenterology Research and Practice،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-469194
Modern Language Association (MLA)
Kaczynski, Jerzy…[et al.]. Increased Porphyrins in Primary Liver Cancer Mainly Reflect a Parallel Liver Disease. Gastroenterology Research and Practice No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-469194
American Medical Association (AMA)
Kaczynski, Jerzy& Hansson, Göran& Wallerstedt, Sven. Increased Porphyrins in Primary Liver Cancer Mainly Reflect a Parallel Liver Disease. Gastroenterology Research and Practice. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-469194
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469194