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The Effect of Bifid Triple Viable on Immune Function of Patients with Ulcerative Colitis
Joint Authors
Li, Guohua
Zeng, Sheng
Lv, Nonghua
Liao, Wangdi
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
To study effect and its mechanism of Bifid Triple Viable for initially treating ulcerative colitis with 5-aminosalicylic acid.
Methods.
82 patients, who were firstly diagnosed as ulcerative colitis, were randomized into experiment group (41 cases, treated with Bifid Triple Viable and Etiasa) and control group (41 cases, treated with Etiasa).
The clinic symptom score, colon mucosa inflammation score, and some immune indices were detected and compared between two groups before and two months after treatment.
Results.
Two months after treatment, the clinical symptom score, colon mucosa inflammation score, and IL-1β expression in colon mucosa decreased significantly (P<0.01), and IL-10 and IgA expressions in colon mucosa increased significantly (P<0.01).
Those differences were more marked in experiment group than control group (P<0.05).
However, peripheral blood T cell subgroup, immunoglobulins, and complements had no significant difference between two groups two months after treatment, but the ratio of peripheral blood CD4+ T cell to CD8+ T cell in experiment group increased more than that in control group (P<0.05).
Conclusion.
Bifid Triple Viable contributed to Etiasa to treat ulcerative colitis in inducing remission period, which was perhaps related to affecting the patient’s immune function.
American Psychological Association (APA)
Li, Guohua& Zeng, Sheng& Liao, Wangdi& Lv, Nonghua. 2012. The Effect of Bifid Triple Viable on Immune Function of Patients with Ulcerative Colitis. Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-469407
Modern Language Association (MLA)
Li, Guohua…[et al.]. The Effect of Bifid Triple Viable on Immune Function of Patients with Ulcerative Colitis. Gastroenterology Research and Practice No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-469407
American Medical Association (AMA)
Li, Guohua& Zeng, Sheng& Liao, Wangdi& Lv, Nonghua. The Effect of Bifid Triple Viable on Immune Function of Patients with Ulcerative Colitis. Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-469407
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469407