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The Newest Hypothesis about Vitiligo : Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Zinc-α2-glycoprotein (ZAG) is a recently identified adipokine, assigned to the chromosome 7q22.1.
It is a multidisciplinary protein, which is secreted in various body fluids.
The ZAG plays roles in lipolysis, regulation of metabolism, cell proliferation and differentiation, regulation of melanin synthesis, cell adhesion, immunoregulation, and so forth.
Vitiligo is the most common depigmenting skin disorder, characterized by acquired, progressive, and circumscribed amelanosis of the skin and hair.
It commonly begins in childhood or young adulthood.
The pathogenesis of this disorder is uncertain, but it appears to be dependent on the interaction of genetic, immunological, and neurological factors.
For the first time, we pointed the probable association between ZAG and vitiligo.
Herein, I have described this association in different views.
By confirming this association, a surprising progression will occur in the treatment of this prevalent debilitating disease.
American Psychological Association (APA)
Bagherani, Nooshin. 2012. The Newest Hypothesis about Vitiligo : Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein. ISRN Dermatology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-469457
Modern Language Association (MLA)
Bagherani, Nooshin. The Newest Hypothesis about Vitiligo : Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein. ISRN Dermatology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-469457
American Medical Association (AMA)
Bagherani, Nooshin. The Newest Hypothesis about Vitiligo : Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein. ISRN Dermatology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-469457
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469457