Chondrosarcoma : With Updates on Molecular Genetics
Joint Authors
Ayala, Alberto G.
Ro, Jae Y.
Cho, Kyung-Ja
Kim, Mi-Jung
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-02-15
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Chondrosarcoma (CHS) is a malignant cartilage-forming tumor and usually occurs within the medullary canal of long bones and pelvic bones.
Based on the morphologic feature alone, a correct diangosis of CHS may be difficult, Therefore, correlation of radiological and clinicopathological features is mandatory in the diagnosis of CHS.
The prognosis of CHS is closely related to histologic grading, however, histologic grading may be subjective with high inter-observer variability.
In this paper, we present histologic grading system and clinicopathological and radiological findings of conventional CHS.
Subtypes of CHSs, such as dedifferentiated, mesenchymal, and clear cell CHSs are also presented.
In addition, we introduce updated cytogenetic and molecular genetic findings to expand our understanding of CHS biology.
New markers of cell differentiation, proliferation, and cell signaling might offer important therapeutic and prognostic information in near future.
American Psychological Association (APA)
Kim, Mi-Jung& Cho, Kyung-Ja& Ayala, Alberto G.& Ro, Jae Y.. 2011. Chondrosarcoma : With Updates on Molecular Genetics. Sarcoma،Vol. 2011, no. 2011, pp.1-15.
https://search.emarefa.net/detail/BIM-469478
Modern Language Association (MLA)
Kim, Mi-Jung…[et al.]. Chondrosarcoma : With Updates on Molecular Genetics. Sarcoma No. 2011 (2011), pp.1-15.
https://search.emarefa.net/detail/BIM-469478
American Medical Association (AMA)
Kim, Mi-Jung& Cho, Kyung-Ja& Ayala, Alberto G.& Ro, Jae Y.. Chondrosarcoma : With Updates on Molecular Genetics. Sarcoma. 2011. Vol. 2011, no. 2011, pp.1-15.
https://search.emarefa.net/detail/BIM-469478
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469478