Collagen Cross-Linking : Current Status and Future Directions
Joint Authors
Hovakimyan, Marine
Stachs, Oliver
Guthoff, Rudolf F.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Collagen cross-linking (CXL) using UVA light and riboflavin (vitamin B2) was introduced as a clinical application to stabilize the cornea by inducing cross-links within and between collagen fibers.
CXL has been investigated extensively and has been shown clinically to arrest the progression of keratoconic or post-LASIK ectasia.
With its minimal cost, simplicity, and proven positive clinical outcome, CXL can be regarded as a useful approach to reduce the number of penetrating keratoplasties performed.
Small case series have also indicated that CXL is beneficial in corneal edema by reducing stromal swelling behavior and in keratitis by inhibiting pathogen growth.
Despite these encouraging results, CXL remains a relatively new method that is potentially associated with complications.
Aspects such as side effects and recurrence rates have still to be elucidated.
In light of the growing interest in CXL, our paper summarizes present knowledge about this promising approach.
We have intentionally endeavored to include the more relevant studies from the recent literature to provide an overview of the current status of CXL.
American Psychological Association (APA)
Hovakimyan, Marine& Guthoff, Rudolf F.& Stachs, Oliver. 2012. Collagen Cross-Linking : Current Status and Future Directions. Journal of Ophthalmology،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-469622
Modern Language Association (MLA)
Hovakimyan, Marine…[et al.]. Collagen Cross-Linking : Current Status and Future Directions. Journal of Ophthalmology No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-469622
American Medical Association (AMA)
Hovakimyan, Marine& Guthoff, Rudolf F.& Stachs, Oliver. Collagen Cross-Linking : Current Status and Future Directions. Journal of Ophthalmology. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-469622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469622