MicroRNA Role in Thyroid Cancer Development
Joint Authors
Luzi, Ettore
Brandi, Maria Luisa
Marini, Francesca
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-10
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
MicroRNAs (miRNAs) are endogenous noncoding RNAs that negatively regulate gene expression by binding the 3′ noncoding region of the messenger RNA targets inducing their cleavage or blocking the protein translation.
They play important roles in multiple biological and metabolic processes, including developmental timing, signal transduction, and cell maintenance and differentiation.
Their deregulation can predispose to diseases and cancer.
miRNA expression has been demonstrated to be deregulated in many types of human tumors, including thyroid cancers, and could be responsible for tumor initiation and progression.
In this paper we reviewed the available data on miRNA deregulation in different thyroid tumors and describe the putative role of miRNA in thyroid cancer development.
American Psychological Association (APA)
Marini, Francesca& Luzi, Ettore& Brandi, Maria Luisa. 2011. MicroRNA Role in Thyroid Cancer Development. Journal of Thyroid Research،Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-469652
Modern Language Association (MLA)
Marini, Francesca…[et al.]. MicroRNA Role in Thyroid Cancer Development. Journal of Thyroid Research No. 2011 (2011), pp.1-12.
https://search.emarefa.net/detail/BIM-469652
American Medical Association (AMA)
Marini, Francesca& Luzi, Ettore& Brandi, Maria Luisa. MicroRNA Role in Thyroid Cancer Development. Journal of Thyroid Research. 2011. Vol. 2011, no. 2011, pp.1-12.
https://search.emarefa.net/detail/BIM-469652
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469652