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Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation
Joint Authors
Eskioglu, Fatma
Akgul, Ahmet
Kartal Durmazlar, Selda Pelin
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-02-01
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
Our aim was to evaluate the significance of homocysteine (Hcy) in Behcet's disease (BD) and the association of elevated Hcy levels associated with the indices of inflammation in BD.
Methods.
Untreated 70 patients with BD and 33 healthy individuals were included into the study.
Hcy, tumor necrosis alpha (TNF-α), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were evaluated with respect to activity and specific individual clinical manifestations of the disease.
Results.
Hcy levels were found significantly elevated in active BD when compared to inactive BD and healthy controls.
Hcy levels were found to have high correlation with the number of active clinical manifestations increased.
A significant positive correlation was found between serum Hcy and TNF-α levels, CRP, and ESR.
Hcy was found to be the best predictor of TNF-α among other parameters.
Conclusion.
Hcy may involve in the pathogenesis of BD by inducing inflammation.
American Psychological Association (APA)
Kartal Durmazlar, Selda Pelin& Akgul, Ahmet& Eskioglu, Fatma. 2009. Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation. Mediators of Inflammation،Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-469743
Modern Language Association (MLA)
Kartal Durmazlar, Selda Pelin…[et al.]. Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation. Mediators of Inflammation No. 2008 (2008), pp.1-9.
https://search.emarefa.net/detail/BIM-469743
American Medical Association (AMA)
Kartal Durmazlar, Selda Pelin& Akgul, Ahmet& Eskioglu, Fatma. Homocysteine May Involve in the Pathogenesis of Behcet's Disease by Inducing Inflammation. Mediators of Inflammation. 2009. Vol. 2008, no. 2008, pp.1-9.
https://search.emarefa.net/detail/BIM-469743
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469743