Current and Emerging Therapeutic Options in Adrenocortical Cancer Treatment
Joint Authors
Sampaoli, Camilla
Cerquetti, Lidia
Toscano, Vincenzo
Stigliano, Antonio
Bucci, Barbara
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-14
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Adrenocortical carcinoma (ACC) is a very rare endocrine tumour, with variable prognosis, depending on tumour stage and time of diagnosis.
The overall survival is five years from detection.
Radical surgery is considered the therapy of choice in the first stages of ACC.
However postoperative disease-free survival at 5 years is only around 30% and recurrence rates are frequent.
o,p’DDD (ortho-, para’-, dichloro-, diphenyl-, dichloroethane, or mitotane), an adrenolytic drug with significant toxicity and unpredictable therapeutic response, is used in the treatment of ACC.
Unfortunately, treatment for this aggressive cancer is still ineffective.
Over the past years, the growing interest in ACC has contributed to the development of therapeutic strategies in order to contrast the neoplastic spread.
In this paper we discuss the most promising therapies which can be used in this endocrine neoplasia.
American Psychological Association (APA)
Stigliano, Antonio& Cerquetti, Lidia& Sampaoli, Camilla& Bucci, Barbara& Toscano, Vincenzo. 2012. Current and Emerging Therapeutic Options in Adrenocortical Cancer Treatment. Journal of Oncology،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-469763
Modern Language Association (MLA)
Stigliano, Antonio…[et al.]. Current and Emerging Therapeutic Options in Adrenocortical Cancer Treatment. Journal of Oncology No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-469763
American Medical Association (AMA)
Stigliano, Antonio& Cerquetti, Lidia& Sampaoli, Camilla& Bucci, Barbara& Toscano, Vincenzo. Current and Emerging Therapeutic Options in Adrenocortical Cancer Treatment. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-469763
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469763