Boron Drug Delivery via Encapsulated Magnetic Nanocomposites : A New Approach for BNCT in Cancer Treatment
Joint Authors
Zhu, Yi Zhun
Lin, Yongxiang
Lu, Jia
Hosmane, Narayan S.
Zhu, Yinghuai
Maguire, John A.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
Ortho-carborane cages have been successfully attached to modified magnetic nanoparticles via catalytic azide-alkyne cycloadditions between 1-R-2-butyl-Ortho-C2B10H10(R=Me,3;Ph,4) and propargyl group-enriched magnetic nanoparticles.
A loading amount of 9.83 mmol boron atom/g starch-matrixed magnetic nanoparticles has been reached.
The resulting nanocomposites have been found to be highly tumor-targeted vehicles under the influence of an external magnetic field (1.14T), yielding a high boron concentration of 51.4 μg/g tumor and ratios of around 10 : 1 tumor to normal tissues.
American Psychological Association (APA)
Zhu, Yinghuai& Lin, Yongxiang& Zhu, Yi Zhun& Lu, Jia& Maguire, John A.& Hosmane, Narayan S.. 2010. Boron Drug Delivery via Encapsulated Magnetic Nanocomposites : A New Approach for BNCT in Cancer Treatment. Journal of Nanomaterials،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-469868
Modern Language Association (MLA)
Zhu, Yinghuai…[et al.]. Boron Drug Delivery via Encapsulated Magnetic Nanocomposites : A New Approach for BNCT in Cancer Treatment. Journal of Nanomaterials No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-469868
American Medical Association (AMA)
Zhu, Yinghuai& Lin, Yongxiang& Zhu, Yi Zhun& Lu, Jia& Maguire, John A.& Hosmane, Narayan S.. Boron Drug Delivery via Encapsulated Magnetic Nanocomposites : A New Approach for BNCT in Cancer Treatment. Journal of Nanomaterials. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-469868
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-469868